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Scientific Sense Podcast

Tuesday, November 21, 2017

Neutrality

As the administration after mammoth efforts to take millions off healthcare, promote big game hunting in Africa, accelerate environmental degradation, and bias a tax code on the pretext of simplification, sets out to dismantle the lifeblood of entrepreneurship in technology by scrapping Net Neutrality, one can only wonder what could be in store next. Ironically, the monopolies who will benefit from the policy change affirmed their intention to continue with the status-quo. But as we have seen before, when the next quarter rolls around and the EPS needs a kick, such altruism will fade quickly.
It has been strange times - logic and science have taken a back seat to racism and hypocrisy. Nearly hundred years of incremental but constant upward slope in societal progress has been turned back in the blink of an eye. This poses an interesting question: Are incremental improvements in societal design really worth it? It has been costly for many, some paid heavily and others took the free ride but it has always been hoped that we are moving forward. It is a bit like making small profits in the stock market and feeling happy about it for a long time only to be wiped out by a discontinuity that cannot be forecasted. The current discontinuity affecting the social fabric will do damage that will take a long time to mend, if at all.
It seems that simply getting "educated," is not enough. A full brain education, designed and executed by few institutions in the US, focus on the individual, not on the content. Nothing good can come out of education unless the carrier has a broad view of the world and the universe. And, that requires multi-dimensional education - science, literature, philosophy, art, music, theatre and more. Education has to lift the psyche of the individual and not her net-worth. This is why I strongly believe only one country in the whole world has gotten it right - Norway. The country that led education forever has turned it upside down to advance to the future, perhaps alone. Education has to be free and flexible - a program that will let the rising hearts and developing brains to design and to make the world better.
We are set too far back in a race that is relentless. The fact that less than a dozen people could do this to destroy the dreams of 330 million souls is inexplicable. But as we have seen in history, the tide could turn again - and this time, we know what to insure against.

Saturday, November 18, 2017

The devil wears Brioni (and a silk tie)

In my book Flexibility (1) I argued 8 years ago that men should not be in positions of complex policymaking. Trained to hunt and gather for hundreds of thousands of years, they do not have the experience to deal with societies that show diversity and differing needs. For most of their life, they spent time fine-tuning process skills and their brains specialized in optimization and not in complexity. But now, they are pushed into jobs they are ill-equipped to do. To make matters worse, they have no clue about it.
Men have been problematic. Their brains appear incapable of understanding interconnectivity and they seem to spend a lot of time counting scores and money. That's appropriate as their incentives have been driven by the quantity of trophies they collect and the mouths they feed. Such was their power they ran over civilizations who have shown trends of progress but they completely arrested any such notion. If humans do not figure this out soon, they could be dragged down by testosterone and ignorance. The outcomes of this movie can only be bad and the fact that the opposite gender is gentle and brainy means that the stalemate is going to continue for a long time.
Men, responsible for most of the ills in the world, appear still to be in charge. It is unclear, why.
(1) https://www.crcpress.com/Flexibility-Flexible-Companies-for-the-Uncertain-World/Eapen/p/book/9781138112391

Sunday, November 12, 2017

All roads lead to autoimmunity

Recent news that (1) Alzheimer’s disease could be caused by a haywire immune system is a constant reminder that the era of seeking external targets and influencing them by chemical means is over. Humans have conclusively proven that they are capable of killing anything that invades their bodies. As they win wars, they seem to have lost the battle as the overriding threat to life now appears to be their own immune systems, marginalized by drugs.
This is a new regime - autoimmune diseases account for most of the health care costs today and drugs that help solve external problems are commoditized and rendered irrelevant. The single cell organisms that made havoc for a few hundred thousand years have been tamed and even bacterial resistance created by the overuse of antibiotics is handled with relative ease. Although the common flu makes impressive comebacks every year, the recent discovery that could result in a long-term vaccine against it, attacking the stem of the virus rather than its head, is welcome news. But, humans have failed to stop their own bodies attacking them and herein lies the conundrum. They seem to win small wars but always lose the battle.
To go further, a dramatic shift is needed in life sciences. Century-old companies, trigger happy and target focused, have to realize that they have to dramatically change their R&D focus. Making incremental improvements to already solved problems, albeit interesting, will not make a difference to healthcare costs or utility. Thier chemistry know-how could be handy, but now perhaps it is time to look inward. The human appears to be a fairly simple machine with a single pump that supplies the lifeblood and a single CPU that makes decisions. The failure of the pump or the CPU is catastrophic and that remains to be the biggest reason for the loss of life. The respiratory system that provides the necessary fuel takes the next biggest share and, here behavior seems to have played a big role just as in the next slice representing the metabolic syndrome channel.
Humans never had "enough," to eat. Their feeble bodies and primitive tools won against the mighty animals only occasionally and their bodies are trained to operate with a few hundred calories a day. But now, they throw out thousands of calories after stuffing themselves with a few more thousand and this has created havoc in their own systems. Their plumbing seems to have been designed badly to start with and now with particles floating in the system that is not capable of eliminating them, their organs are failing. And their bodies and immune system, confused and lethargic, are attacking them.
To make further advancements in health, knowledge, and culture, humans have to figure out how not to lose to themselves.
(1) https://www.alzheimers.net/5-11-16-early-alzheimers-caused-by-haywire-immune-system/