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Monday, August 8, 2016

Premature existence

Recent ideas from Harvard (1) speculate on the lack of  maturity of life as we find it on Earth. Contemporary theory, which appears highly unlikely to be true, suggests an origin of the universe about 14 billion years ago and the ultimate demise of it in about ten trillion years from now, making it infinitesimally closer to birth than death. Life, if it is a property of the system, has had only a short moment in this unimaginably long time horizon. So prototypical observations of life, such as that we find on this uninteresting corner of the Milky Way, a rather common place galaxy, is premature by any stretch of the imagination. Even after the Sun balloons up in less than five billion years to a red giant and consumes the blue planet, with all its ignorance locked up in a small space, the universe will continue and create life forms of much greater capabilities and interest.

Life on Earth appears to show severe limitations and indicate prototypical experimentation, with infinitesimal life spans of biological units, that appear incapable of perpetuating information and knowledge across time. Such a design can only be the result of an unsuccessful trial of a large number of possible simulations. The fact that "advanced life," is battling the microscopic ones on Earth can only imply very early and unsophisticated experiments to gather raw data. If there is any learning present in this prototypical system, it has to be about what does not work rather than the other way around. The fact that the blue planet at the exact distance from a medium size star with such abundant resources and stable climate has been unable to produce intelligence may instruct future experiments, what not to attempt.

It is early but known experiments appear to be in the wrong direction.

(1) http://esciencenews.com/articles/2016/08/01/is.earthly.life.premature.a.cosmic.perspective

Tuesday, August 2, 2016

Biology meets computing

The ease of biological manipulation by chemical means has held life sciences companies back for over a century from exploring the system, that is equally receptive to electromagnetic interventions. Recent news that GSK has partnered with Alphabet to advance the field of bioelectronics is encouraging. The idea is to impart electrical signals to neurons by micro implants to cure chronic diseases. Although it is a profitable path to pursue, some caution may be in order.

There is a long history of engineering experts attempting prescriptive interventions on biological systems with an expectation of deterministic outcomes. Humans are generally good in engineering and traditional computing but biological systems do not behave in such a predictable fashion. Their engineering competence comes from selection, in which simple tools based on Newtonian Physics let them survive the harsh environment they were in for nearly hundred thousand years. The modern game is distinctly different and it is unlikely that they possess the skills to fast track with the hardware they have built up. With "Artificial Intelligence," soaking up the air waves, it is important for technology giants to bias toward humility. As projects such as "death cure," so slow to come to fruition so as to annoy the technologists behind it, perhaps getting not too excited about curing diabetes through neuron stimulation is a good idea. After all, nature took four billion years to get here, albeit, it was without a computer farm that soaks up a high share of the world electricity production. Competing with nature is likely to take a bit more than that.

The convergence of biology and computing is unavoidable. However, it is unlikely to be advanced by those with stagnant notions of either field.

Sunday, July 31, 2016

The inverted U

The value individuals add to society appears to be in the shape of an inverted U. On the high end - philosophers, scientists and technologists, who seem to know everything, appear to add very little of practical value. Recently, a scientist remarked, "when we found the gravity waves, the whole world stopped," unaware of the fact that most of the world did not know or care. On the low end, ignorance is as dangerous as cyanide, as ably demonstrated by contemporary politicians. In this scheme, the highest value to society appears to come from those in the middle - not too ignorant and not too arrogant. On both ends, there is a common factor - a brain that is idle, because of either stupor or conceit.

To maximize the value that individuals contribute to society, it appears that they have to be lifted from the abyss of ignorance or shown a practical path down from the mountains. The perception of knowledge is as dangerous as a lack of awareness of ignorance - for both result in a loss of value to society by a lack of contribution. The former, locked behind ivy walls, lament at a world of ignorance and the latter, aided and abetted by their leaders, scorn at knowledge. In the middle, humans of blood and flesh, are caught in a time warp they simply could not escape. Apathetic and lethargic, the middle withdraw from media events and elections and watch from the sidelines. This is a movie with a sad ending - dominated either by the ignorant or the arrogant, with little to differentiate between them.

Neither abundance nor lack of knowledge add societal value. Those who are aware of their limitations, do.


Wednesday, July 27, 2016

Simplified diagnostics

Research from Columbia (1) indicates that impairment in odor identification portends cognitive decline and possibly Alzheimer's disease. This appears to dominate more prevalent PET and MRI scans for the diagnosis of these ailments. This is a constant reminder that humans are far from mastering the workings of the organ they carry on their shoulders by engineering and scientific means and simpler measurements of inputs and outputs dominate such mechanics.

The human brain has been an enigma. It consumes vast amounts of energy and often produces little utility - either to the immediate host or to society at large. It effectively delegates routine affairs to the vast Central Nervous System attached to it by a thread and maintains a small garbage collection mechanism within itself to keep track of the estate it manages, automatically. Often, it gets bored and shows signs of over-design, a quirk of evolution that endowed it with vast processing power by incorporating quantum computing in a small and efficient space. Lack of large memory has allowed it to venture into the production of heuristics and showing signs of intelligence. But acceleration in technology and society has stretched it, lending some functions of importance irrelevant and elevating the irrelevant to importance.

Its decline is painful to close observers but not necessarily so for the host, herself. In a regime that disallows rolling back time, the objective function has to be minimizing pain - physical or emotional. A system that pragmatically allows such an outcome by its own deterioration can only be considered good. Diagnostics that does not require cutting open the delicate organ or injecting it with radioactive materials may be the best, for the recognition of the start of decline of this beautiful machine is not necessarily good for the host nor for close observers.

(1) http://esciencenews.com/articles/2016/07/27/smell.test.may.predict.early.stages.alzheimers.disease