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Scientific Sense Podcast

Thursday, March 28, 2019

F-Theory, Occam's razor and ignorance

Physicists are funny people - they like complexity and large numbers. They recently found F-theory (not sure what "F" stands for except for the obvious possible guesses), that demonstrates a "quadrillion ways, string theory could make the universe." That is impressive and could provide rich fodder for PhD theses and "peer reviewed," publications for a century to come. But does it advance knowledge? It is less clear.

Complexity is a problematic concept. As the true geniuses of the yesteryear correctly emphasized, "God does not play dice," and unless she has a quantum computer in the basement, she will not embark on a journey that has "quadrillion," ways to make the universe. Large numbers could be ego boosting behind the ivy walls but it has no practical use. It is probably time for those attempting to formulate the next exotic "theory of everything," to get out of their windowless offices and smell the roses.

There is no problem that has been solved by increasing complexity. Those who advanced thinking always preferred simplicity. Knowledge is clearly inversely correlated with complexity. Even the money men, who typically do not know much, seem to have gravitated to this universal law. So, why are we here at this point in time? One possible answer is that engineering heavy education has churned out engineers who want to measure "reverberations," not much larger than the size of a proton or mathematicians, enamored by "large numbers." Even the business guys seem to have learned bad habits as most want to use, "big data."

Complexity is utility diminishing. Theories that push in that direction is utterly useless.

(1) https://www.scientificamerican.com/article/found-a-quadrillion-ways-for-string-theory-to-make-our-universe/

Tuesday, March 26, 2019

The era of bioelectronics

The most complex electromagnetic and chemical system known, the human body, so far has substantially avoided manipulation by electromagnetic means. This may be changing. Recent news (1) about a transistor design that enables integrated, real-time sensing and simulation of signals from living organisms, could lead to better diagnostics and treatment. Low cost Silicon has impeded innovation and applications in non-conventional substrates. There have been few biocompatible designs for the lack of appropriate materials and incentives.

Chemicals have been easier and in the presence of many low hanging fruits, researchers did not spend much time on alternatives. As they solved simpler problems, auto-immune diseases start to dominate the human architecture. The heart-breaking failure of a recent drug for Alzheimer's (2) is symptomatic of the end of the chemical era. The brain likely responds better to electromagnetic stimuli but contemporary pharmaceutical companies are ill-equipped to pursue this line of thought.

Simple diseases such as Hypertension and Type 2 Diabetes, that command over half of the healthcare costs in the log run, could be positively influenced by better monitoring and treatment mechanisms that are integrated into the body. CHF and other Cardiovascular events could be picked up earlier and intervened optimally by the same mechanisms. As the sun gets hotter and nastier, embedded devices in the skin could shield the body from harmful rays. Organ failures could be arrested, nutrition deficiencies could be remedied, better food and treatment regimens could be suggested and humanity could possibly move to a more advanced health regime.

It is exciting. Integrated bioelectronics with embedded artificial intelligence could be a game changer.

(1) http://advances.sciencemag.org/content/5/2/eaau7378
(2) https://www.cnn.com/2019/03/21/health/alzheimers-drug-trial-failure-aducanumab-bn/index.html