Saturday, September 22, 2018

Gut feel

A recent finding (1) that shows that the gut uses a variety of communication channels to rapidly communicate with the brain has implications for the prevention and treatment of many diseases, including obesity and the metabolic syndrome spectrum. Many had this intuition but now hard data is showing that humans are driven largely by their gut with the brain playing the role of a computer, merely calculating and shuttling instructions. This is not surprising. For over half a million years, they sought food for survival and the gut and its occupants, the constituents of the microbiome, have been reigning supreme. The overgrown appendage, the brain, serves little purpose in the grand scheme of things.

The recent reversal of roles has the brain scrambling to divide itself into two halves - the tactical and the strategic. Enormous excess capacity allows it to process ancient rules and instructions without breaking a sweat. The ensuing boredom has led it to seek utility from abstract ideas such as art, music, and literature. With science and technology in the background, not requiring significant processing power, the brain can float above triviality and the routine.

This is problematic. An organ, largely intended as a conventional computing resource, is wasting itself, getting involved in thought experiments, at least from the perspective of the gut. A bifurcating human architecture, still fundamentally managed by the microbiome in the gut, coupled with a confusing potpourri of capabilities upstairs, could portend disaster. The toys they have invented are now growing into entities without guts and that will certainly pose a challenge to the declining species.

The decline of the advanced entity is predictable but that has implications for the most successful species for nearly 5 billion years. A world controlled by silicon and light will be bad news for the microbiome. It is unlikely that the species that dominates the universe will let that happen.